apalutamide will decrease the level or influence of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of apalutamide, a solid CYP3A4 inducer, with medications that happen to be CYP3A4 substrates may end up in reduced publicity to those drugs.Modafinil appeared to make a focu
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